The Surprising Connection Between Uric Acid and Cardiovascular Health

Dr. Kristie Gering • July 3, 2023

Dr. Kristie, dietitian Chelsi, and health coach Cheryl recently attended a thought-provoking conference on cardiometabolic disease where they encountered a captivating discussion on the role of uric acid in cardiovascular health. Spearheaded by renowned author and physician, Dr. David Perlmutter, the conversation shed light on the importance of maintaining optimal uric acid levels and its impact on our overall well-being.

Traditionally, uric acid has been primarily associated with gout, a painful form of arthritis. However, emerging research suggests this compound may have far-reaching implications beyond its well-known role in joint inflammation. Uric acid, a byproduct of purine metabolism, is typically filtered by the kidneys and excreted through urine. When levels of uric acid in the blood become elevated, it can lead to a condition called hyperuricemia.


Cardiovascular disease remains a leading cause of mortality worldwide. Often dubbed the "silent killer," it encompasses a wide range of conditions affecting the heart and blood vessels. Examples include coronary artery disease, heart attacks, and strokes. Identifying novel markers for cardiovascular risk assessment has been a crucial area of research, and recent findings have highlighted uric acid as a potential candidate.


During the cardiometabolic disease conference, Dr. David Perlmutter captivated the audience with his enlightening presentation on the significance of uric acid levels in relation to cardiovascular health. Dr. Perlmutter's book, Dropping Acid, delves into the topic, offering valuable insights into the management of uric acid levels.


Research suggests elevated uric acid levels may contribute to the development and progression of cardiovascular disease. Studies have shown a correlation between hyperuricemia and conditions such as hypertension, atherosclerosis, and heart failure. While the exact mechanisms behind this association are still being explored, several theories have emerged.


One theory proposes that elevated uric acid levels contribute to endothelial dysfunction, impairing the delicate lining of blood vessels. This dysfunction can lead to the formation of plaques, restricted blood flow, and increased risk of heart attacks and strokes. Additionally, uric acid may promote inflammation and oxidative stress, further exacerbating cardiovascular damage.


Given the potential role of uric acid in cardiovascular disease, maintaining optimal levels may have significant implications for our heart health. Lifestyle modifications, such as adopting a diet lower in purines (found in certain foods like red meat and seafood), sugar (especially high fructose corn syrup), and alcohol, may help decrease uric acid levels. Regular exercise, weight management, increasing fiber, and adequate hydration also play essential roles in mitigating hyperuricemia.


Furthermore, certain supplements such as tart cherry extract may help lower uric acid. A number of medications, including aspirin, diuretics, beta-blockers, and ACE inhibitors can result in higher uric acid loads. However, certain medications such as xanthine oxidase inhibitors, can lower uric acid levels by inhibiting the enzyme responsible for its production. However, it is crucial to consult a healthcare professional for guidance on supplement/medication usage and potential side effects.


The relationship between uric acid and cardiovascular disease represents an intriguing area of research within the healthcare community. As healthcare professionals delve deeper into understanding this connection, it is becoming increasingly evident that uric acid levels serve as an important marker for cardiovascular risk assessment. Dr. David Perlmutter's insightful discussion and his book Dropping Acid serve as valuable resources for professionals and individuals seeking to optimize cardiovascular health.


If you are interested in checking your uric acid level, it can be done with a simple blood test. The goal for cardiovascular health is to achieve a level <7.0. If your level is higher, you are invited to make an appointment with health coach Julie Petranovitch or registered dietitian Chelsi Webster to explore ways to lower uric acid naturally. If still not at goal, we can explore ways to decrease your need for diuretics and antihypertensives (if applicable) and add supplements and/or possibly medication to help. You are welcome to call us at 715-861-2300 to schedule a lab visit and/or learn more about our coaching/nutrition services.

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Bone Turnover Tests, Peptides, and Smarter Ways to Track Bone Health

By Dr. Kristie Gering • April 20, 2026
Bone health is more than a DEXA scan. Learn how CTX & P1NP blood tests, peptides, and REMS imaging help track bone loss and response to treatment earlier.

Why "Thick Blood" Isn't the Whole Story

By Dr. Kristie Gering • February 16, 2026
Many people with chronic symptoms are told their labs are “normal,” yet they still feel unwell. One overlooked reason is excess fibrin , a sticky structural protein your body naturally makes to heal injuries. It’s what happens when too much fibrin builds up over time and/or when your body can't break it down fast enough. Think of fibrin like scaffolding In small amounts, fibrin helps healing In excess, it can: Form protective shells (biofilms) around bacteria or viruses Hide infections from antibiotics and the immune system Stiffen blood vessels Interfere with circulation and healing This can help explain why some infections or symptoms never fully go away . Why does fibrin build up? There are two main reasons: 1. Some people make too much fibrin This can be genetic or driven by chronic inflammation (infections, mold exposure, autoimmune conditions). 2. Some people don’t break fibrin down well Their bodies don’t activate the enzymes needed to dissolve excess fibrin. Many people have both problems at once. How this can affect health Excess fibrin has been linked to: Chronic or recurrent infections Long COVID symptoms Brain inflammation (PANS/PANDAS) Fatigue and pain syndromes Pregnancy loss Heart and blood vessel disease Importantly, standard clotting tests often don’t detect this because they’re designed for emergencies, not slow buildup over years. Why treatment must be gentle and personalized Breaking down fibrin too quickly can: Release trapped toxins or microbes Increase inflammation temporarily Make symptoms flare That’s why the goal is balance , not “thinning the blood.” When done correctly, fibrin support: Helps the immune system see hidden infections Improves response to other treatments Supports long-term healing rather than short-term suppression Key Takeaway If you’ve tried “everything” and still feel stuck, the issue may not be what you’re treating - rather w hat’s been blocking your body from clearing it. Excess fibrin may be that missing piece. Action Plan If you think this may apply to you: Request the Hypercoag Reflexive3 Panel (Labcorp Test Code: 505443) Set up an appointment with your provider to discuss the results. Resources for Further Information: https://www.betterhealthguy.com/episode207 https://canadarna.com/products/boluoke-lumbrokinase Episode #207: Hypercoagulation with Ruth Kriz, MSN, APRN - BetterHealthGuy.com After nearly thirty years since the start of a serious chronic illness, BetterHealthGuy.com chronicles my journey through and recovery from Lyme Disease, mold illness, and the myriad of issues chro...
NAD Drip, Chippewa Falls

Feeling tired? Try an NAD Infusion

December 1, 2023
Want help to get ready for the holidays? Having difficulty adjusting to the time change? Consider an NAD Infusion. What are the benefits? NAD+ (nicotinamide adenine dinucleotide) is a coenzyme that powers metabolic processes and impacts a wide variety of systems including digestion, cognition, mental clarity, aging, and overall energy levels. ​ NAD+ increases our body’s levels of serotonin, a neurotransmitter associated with mood regulation, and can improve symptoms of depression and anxiety. NAD+ plays a role in cell health and in hundreds of cell functions such as DNA repair, circadian rhythm, metabolism, muscle function, tissue repair and cognitive function. Basically, our cells require NAD+ to quickly shuttle around electrons - keeping the cells buzzing with the electricity of life! ​ Who is it for? NAD+ is the premier IV drip for clients who want to see major improvements in brain function, energy level, overcome anxiety and depression, handle acute and chronic stress more effectively, and cope better with PTSD. ​ What's inside? We administer 250mg or 500 mg of NAD+ in an IV drip. (We always start with 250mg the very first time you try it.) ​ How often? For best results, NAD+ may need several sessions depending on personal needs. The number of sessions will be discussed during an initial encounter. The NAD+ IV drip does take longer to receive than any other IV drip. Each session may last from 2.5 to 4 hours, depending on the tolerance. During the infusion, an individual might feel a bit of discomfort compared to standard vitamin drips - described as a bit of a rush through the body, but this is completely normal and can be controlled by how fast the IV is set to drip and stops within a minute or two after the drip ends. ​ Our NAD+ drip can be followed by Glutathione -"Master Antioxidant " - for best results. Fall 2023 Special - 250mg is $250 and 500mg is $350. Glutathione 1g added on after the infusion is $35.00.